Home

Ted Holman's Lab logo - the protein lipoxygenase is in blue and red with the iron at the active sites as a yellow circle in the middle.

NEW FRONTIERS IN BIOCHEMISTRY TO IMPROVE LIVES

Welcome to the Holman Laboratory, a place of biochemical discovery bridging biology and chemistry. Our research team studies the family of enzymes called lipoxygenases (LOX), an enzyme pivotal in human health. Utilizing diverse techniques such as enzymology, molecular biology, site-directed mutagenesis, and mass spectroscopy, we discover the intricate role of LOX in critical biological processes and its link to diseases, including blood coagulation, heart disease, and diabetes. Our lab is renowned for its groundbreaking work identifying new LOX inhibitors and pioneering research on its allosteric regulation. Collaborating with top-tier scientists, we aim to transform our discoveries into innovative therapies and solutions. At the Holman Laboratory, we’re not just conducting research; we’re charting new frontiers in biochemistry to improve lives and advance medical science.